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DRSC
>> Reagents
Currently Available Reagents at the DRSC
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The DRSC 2.0 library for genome-wide screening is currently the most commonly used reagent. Approximately 13,900 genes covered (updated regularly). On-site screening only.
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The DRSC Validation library covers all gene hits from previous screens (approaching genome-wide coverage). The amplicons cover different gene regions than those covered with DRSC 2.0.
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We have a growing collection of smaller dsRNA libraries for RNAi screening that are based on curated lists of related genes. Kinase/phosphatases, transcription factors, and more.
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We have a growing collection of UAS constructs for over-expression. In collaboration with the modENCODE group, our primary focus is on non-coding RNAs (including miRNAs).
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Currently in progress, the Transgenic RNAi Project (TRiP) for generation of hairpin fly lines.
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Note: To design an RNAi construct for one or a few genes, please visit our on-line SnapDragon tool. For cell lines, see this page. FlyBase maintains a list of other material resources here.
For more information on a specific collection, please click on the appropriate image in the table above.
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