Drosophila RNAi Screening Center

DRSC >> Reagents

Currently Available Reagents at the DRSC

DRSC 2.0 The DRSC 2.0 library for genome-wide screening is currently the most commonly used reagent. Approximately 13,900 genes covered (updated regularly). On-site screening only.
DRSC Validation The DRSC Validation library covers all gene hits from previous screens (approaching genome-wide coverage). The amplicons cover different gene regions than those covered with DRSC 2.0.
RNAi Sub-Libraries We have a growing collection of smaller dsRNA libraries for RNAi screening that are based on curated lists of related genes. Kinase/phosphatases, transcription factors, and more.
UAS-Gene Libraries We have a growing collection of UAS constructs for over-expression. In collaboration with the modENCODE group, our primary focus is on non-coding RNAs (including miRNAs).
Transgenic RNAi Project Currently in progress, the Transgenic RNAi Project (TRiP) for generation of hairpin fly lines.

Note: To design an RNAi construct for one or a few genes, please visit our on-line SnapDragon tool. For cell lines, see this page. FlyBase maintains a list of other material resources here.

For more information on a specific collection, please click on the appropriate image in the table above.